Do women stay “mentally sharp” for longer than men?

Scientists and doctors have long believed that women’s and men’s brains age differently.

Now researchers have shown that time does affect women and men’s brains differently – men’s brains diminish more quickly than women’s.

As men and women age, their brain size shrinks, and the rate of brain metabolism slows.

Researchers set out to find out exactly how this rate of metabolism changes over time – a factor that could influence how vulnerable someone is to neurodegenerative diseases such as dementia.

The study

A study of 200 men and women, ranging in ages from 20 to 82 years, underwent PET scans to measure the flow of oxygen and glucose to their brains.

The scientists looked at the fraction of sugar committed to aerobic glycolysis – a process associated with metabolism – in different regions of the brain.

The scientists then developed an algorithm to determine the relationship between chronological age and brain metabolism. They calculated the rate for men, and then fed the women’s data into the algorithm.

According to the findings, recently published in the Proceedings of the National Academy of Sciences of the United States of America, women’s brains were on average 3.8 years younger than suggested by their brain metabolism.

They then performed the same calculations but starting with the women’s data, and then feeding the men’s data into the equation. They found that men’s brains were 2.4 years older than their actual age.

Could explain why women stay “mentally sharp” for longer

A statement from the Washington University School of Medicine in St.Louis said the findings could explain by women tend to stay “mentally sharp” for longer than men.

Senior author of the study, Manu Goyal, MD, an assistant professor of radiology and assistant professor of neurology and of neuroscience at the university’s Mallinckrodt Institute of Radiology, said, “We’re just starting to understand how various sex-related factors might affect the trajectory of brain aging and how that might influence the vulnerability of the brain to neurodegenerative diseases.”

Brains are fuelled by sugar, but how that fuel is used changes as our bodies age. Babies and children use aerobic glycolysis for brain development, and the rest of the sugar is used for thinking and doing. In young adults, much of the sugar is used for aerobic glycolysis, but the proportion declines over time, and is in low amounts by the time people are in their 60s.

“Women don’t experience as much cognitive decline in later years”

The study found that men’s brains actually begin adulthood about three years ahead of women’s, and the gap remains as both men and women age.

“It’s not that men’s brains age faster – they start adulthood about three years older than women, and that persists throughout life,” said Goyal.

“I think this could mean that the reason women don’t experience as much cognitive decline in later years is because their brains are effectively younger, and we’re currently working on a study to confirm that.”

The statement from the University said older women tended to score better than men of the same age on reason, memory and problem solving tests.

The researchers will now examine if those with younger looking brains are less likely to develop cognitive problems over the course of their lives.

It’s interesting to note that even though women’s brains may appear to be younger than men’s in some aspects, more women are diagnosed with dementia than men.

According to Dementia Australia, women account for 64 per cent of all dementia-related deaths in Australia. This may be related to the fact that women live longer.

In conclusion

So, what is the answer to the question, ‘Do women say mentally sharp for longer than men?’

According to this study, which admittedly only had a small sample size, the answer appears to be ‘yes’.

Please note: The image used to illustrate this article does not refer to actual people or events. Image: iStock.

Leave a Reply

Your email address will not be published. Required fields are marked *


Top doctor on the verge of tears as 63 Victorian aged care homes now infected

  Health authorities have revealed the coronavirus outbreak has now spread to 63 aged care facilities across the state of Victoria.  It is believed that 170 residents and 146 staff members at residential homes have tested positive, along with four elderly people and six staff members involved with in-home services. Today, Victorian Premier Daniel Andrews... Read More

How the Arts can contribute to quality of life for the elderly

The arts have always been associated with genius and brilliant minds – people like Mozart, Picasso and Shakespeare. But what about using art as a therapy to help the minds of the elderly? Though it won’t cure conditions such as Dementia or Parkinson’s, it has the ability to help people by bringing them some joy... Read More

Search for brave strangers who leapt onto train tracks to rescue a man in wheelchair

The daughter of a 62-year-old man who accidentally fell onto train tracks while driving his electric wheelchair is hoping to contact the brave strangers that rescued her father in Melbourne's northern suburbs. Read More